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A new Paradigm on Acid Reflux

Every day, 70 million people in the United States suffer from digestive problems like
heartburn, acid reflux, indigestion, constipation and diarrhea. Many turn to prescription drugs to control the acid in their stomachs, but some doctors say acid isn’t the problem.

“It’s very simple; we’re not digesting our food,” Mayer Eisenstein, M.D., medical director of Homefirst Health Services and host of the weekly XM satellite radio show The Dr. Mayer Eisenstein Radio Show, told Ivanhoe. He says adding digestive enzymes and probiotics to our diets can help solve this issue. According to Dr. Eisenstein, the body has a limited supply of
digestive enzymes and every 10 years, we lose about 13 percent of them. Western diets also typically consist of cooked and processed food, which can further deplete enzymes. Probiotics, or lactic acid bacteria, can help digest dairy products as well as nutrients like folic acid, riboflavin and vitamin B12, Dr. Eisenstein says.

Using enzymes, probiotics and stevia -- a natural sweetener which has also been show to aid in heartburn -- Dr. Eisenstein created a chewable tablet that he estimates has helped up to 98 percent of the 5,000 patients he’s treated with it. To also aid in digestion, he recommends people eat slower, cook foods less thoroughly and chew sugarless gum after a meal, which has been shown to ease acid reflux. He also says not to drink fluids during a meal, which can wash food into the stomach before the enzymes in saliva break it down.

Proton pump inhibitors (Nexium, Prevacid, Prilosec) -- a type of acid-reducing medication -- are supposed to be prescribed for only two months, but, according to Dr. Eistenstein, the average patient uses them for five years. Dr. Eisenstein says he never prescribes antacid drugs to his patients because they have been shown to increase the risk of developing pneumonia and, in people over 50, increase the incidence of breaking a hip.



SOURCE: Ivanhoe interview with Mayer Eisenstein, M.D.; 16th Annual World Congress on Anti-Aging Medicine &
Regenerative Biomedical Technologies in Orlando, Fla., April 23 - 27, 2008
 Copyright: Ivanhoe 2008

 
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Insulin, Aging and Long Life

Insulin, Aging and Long Life
(Ivanhoe Newswire) -- It may not be the fountain of youth, but new research on insulin shows it plays an important role in aging and lifespan.

Researchers at the Joslin Diabetes Center in Irvine, Calif., report insulin inhibits a master gene regulator protein called SKN-1; increased SKN-1 activity increases lifespan, according to researchers.
“The major implication is that we have found something new that affects lifespan and aging and an important new effect that insulin and/or a related hormone called insulin-like growth factor-1 may have in some tissues,” T. Keith Blackwell, M.D., Ph.D., senior investigator at Joslin Diabetes Center and an associate professor of pathology at Harvard Medical School and a faculty member at the Harvard Stem Cell Institute, was quoted as saying. “The implications go far beyond diabetes.”

Dr. Blackwell, who is also the author of the paper, adds that fine tuning SKN-1 could also lead to increased resistance to other chronic diseases.These findings came as a result of experiments done on a microscopic worm often used as a model organism.
Researchers found SKN-1 controls a network of genes that defend cells and tissue against damage from free radicals and environmental toxins. “You can manipulate the expression of SKN-1 and the worms live longer,” Dr. Blackwell said.

The experiments will be repeated in mammals, but according to Dr. Blackwell, other findings from this particular worm model have turned out to be applicable to mice and humans.

 

SOURCE: Cell, 2008;132:1025-1038
 

Copyright: Ivanhoe 2008


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Leaves Found to Protect the Liver

 
A plant found in the mountains of China and Russia may one day have a role to play in protecting the liver from damage.

A new study out of India suggests the leaves from the sea buckthorn can help keep the liver functioning properly, even when a liver damaging agent is injected into the organ.

The research was carried out in rats that were divided into six different groups. The first group received a harmless saline solution for five days and served as the control group. The second group received saline for four days, then was given an injection of carbon tetrachloride (CCI4) -- a known liver damaging agent. The third group received a daily dose of silymarin (milk thistle extract, which is thought to have a positive effect on the liver) for five days, followed by CCI4. And the final three groups received varying doses of the sea buckthorn leaf extract for five days before being injected with CCI4.

Rats who didn’t receive the leaf extract before being injected with CCI4 suffered significant liver damage, while those who received the two highest doses of the extract (100 milligrams and 200 milligrams) had only minimal damage from the CCI4.

Previous research linked the berries of the sea buckthorn plant to lower cholesterol, but this is the first study to identify a health role for the leaves, although doctors have long known the plant is rich in healthful components like antioxidants and essential fatty acids.

 

SOURCE: Journal of the Science of Food and Agriculture, published online May 23, 2008
Copyright: Ivanhoe 2008

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